plantMetabolomicsProject

A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms
http://metadb.riken.jp/db/plantMetabolomics/0.1/Project/RPMM0030

A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms

Project

projcet ID
  • RPMM0030
title
  • A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms
description
  • We report a computational approach (implemented in MS-DIAL 3.0; http://prime.psc.riken.jp/) for metabolite structure characterization using fully <sup>13</sup>C-labeled and non-labeled plants and LC–MS/MS. Our approach facilitates carbon number determination and metabolite classification for unknown molecules. Applying our method to 31 tissues from 12 plant species, we assigned 1,092 structures and 344 formulae to 3,604 carbon-determined metabolite ions, 69 of which were found to represent structures currently not listed in metabolome databases.
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  • Chiba University the GP Program
  • JST the Strategic International Collaborative Research Program
  • KAKENHI (JSPS 15K01812, 15H05897, 16H06454, 17H03621, 18H02432, 18K19155; MHLW 30190401)
  • Netherlands Organization for Scientific Research
  • JST the Strategic International Research Cooperative Program
  • 'Learning from Nature' program funded by the Dutch Technology Foundation
  • NUE-CROPS project funded by the FP7-CP-IP Research Infrastructures Program of the European Union
  • JST National Bioscience Database Center
  • the European Plant Phenotyping Network (EPPN) funded by the FP7 Research Infrastructures Program of the European Union
  • MAFF Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries and Food Industry
  • Centre of BioSystems Genomics
  • Japan Advanced Plant Science Network
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